The term chemotherapy, which literally means chemical therapy or chemical treatment, was coined in 1913 by Paul Ehrlich, the father of modern chemotherapy. He defined chemotherapyas the use of chemicals (drugs) to injure or destroy infections micro-organisms without causing any injury to the host.
Antipyretic is a drug which is responsible for lowering the temperature of feverish body. The central nervous system, especially the hypothalamus, plays an important role in maintaining the balance between the heat production and heat loss in order to regulate the body temperature. Hypothalamus is, thus,known as the thermostat of the body.
The antipyretic drug helps to reset the thermostat at normal temperature. Heat production is not inhibited but heat loss is increased by increased peripheral blood flow which increases the rate of perspiration. This causes body to lose heat and subsequentlylowers the body temperature.