Friday 29 January 2016

Zika Virus

Zika virus disease: Questions and answers



Where does Zika virus occur?

Zika virus occurs in tropical areas with large mosquito populations, and is known to circulate in Africa, the Americas, Southern Asia and Western Pacific.

Zika virus was discovered in 1947, but for many years only sporadic human cases were detected in Africa and Southern Asia. In 2007, the first documented outbreak of Zika virus disease occurred in the Pacific. Since 2013, cases and outbreaks of the disease have been reported from the Western Pacific, the Americas and Africa. Given the expansion of environments where mosquitoes can live and breed, facilitated by urbanisation and globalisation, there is potential for major urban epidemics of Zika virus disease to occur globally.

How do people catch Zika virus?

People catch Zika virus by being bitten by an infected Aedes mosquito – the same type of mosquito that spreads dengue, chikungunya and yellow fever.

What are the symptoms of Zika virus disease?

Zika virus usually causes mild illness; with symptoms appearing a few days after a person is bitten by an infected mosquito. Most people with Zika virus disease will get a slight fever and rash. Others may also get conjunctivitis, muscle and joint pain, and feel tired. The symptoms usually finish in 2 to 7 days.

What might be the potential complications of Zika virus?

Because no large outbreaks of Zika virus were recorded before 2007, little is currently known about the complications of the disease.

During the first outbreak of Zika from 2013 - 2014 in French Polynesia, which also coincided with an ongoing outbreak of dengue, national health authorities reported an unusual increase in Guillain-Barré syndrome. Retrospective investigations into this effect are ongoing, including the potential role of Zika virus and other possible factors. A similar observation of increased Guillain-Barré syndrome was also made in 2015 in the context of the first Zika virus outbreak in Brazil.

In 2015, local health authorities in Brazil also observed an increase in babies born with microcephaly at the same time of an outbreak of Zika virus. Health authorities and agencies are now investigating the potential connection between microcephaly and Zika virus, in addition to other possible causes. However more investigation and research is needed before we will be able to better understand any possible link.

Should pregnant women be concerned about Zika?

Health authorities are currently investigating a potential link between Zika virus in pregnant women and microcephaly in their babies. Until more is known, women who are pregnant or planning to become pregnant should take extra care to protect themselves from mosquito bites.

If you are pregnant and suspect that you may have Zika virus disease, consult your doctor for close monitoring during your pregnancy.

What is microcephaly?

Microcephaly is a rare condition where a baby has an abnormally small head. This is due to abnormal brain development of the baby in the womb or during infancy. Babies and children with microcephaly often have challenges with their brain development as they grow older.

Microcephaly can be caused by a variety of environmental and genetic factors such as Downs syndrome; exposure to drugs, alcohol or other toxins in the womb; and rubella infection during pregnancy.

How is Zika virus disease treated?

The symptoms of Zika virus disease can be treated with common pain and fever medicines, rest and plenty of water. If symptoms worsen, people should seek medical advice. There is currently no cure or vaccine for the disease itself.

How is Zika virus disease diagnosed?

For most people diagnosed with Zika virus disease, diagnosis is based on their symptoms and recent history (e.g. mosquito bites, or travel to an area where Zika virus is known to be present). A laboratory can confirm the diagnosis by blood tests.


Sugar gel helps premature babies

'Sugar gel' helps premature babies

Around the globe each year 15 million babies are born too soon
A dose of sugar given as a gel rubbed into the inside of the cheek is a cheap and effective way to protect premature babies against brain damage, say experts.
Dangerously low blood sugar affects about one in 10 babies born too early. Untreated, it can cause permanent harm.
Researchers from New Zealand tested the gel therapy in 242 babies under their care and, based on the results, say it should now be a first-line treatment.
Their work is published in The Lancet.
Sugar dose
Dextrose gel treatment costs just over £1 per baby and is simpler to administer than glucose via a drip, say Prof Jane Harding and her team at the University of Auckland.
Current treatment typically involves extra feeding and repeated blood tests to measure blood sugar levels.
But many babies are admitted to intensive care and given intravenous glucose because their blood sugar remains low - a condition doctors call hypoglycaemia.
The study assessed whether treatment with dextrose gel was more effective than feeding alone at reversing hypoglycaemia.
Neil Marlow, from the Institute for Women's Health at University College London, said that although dextrose gel had fallen into disuse, these findings suggested it should be resurrected as a treatment.
We now had high-quality evidence that it was of value, he said.
Andy Cole, chief executive of premature baby charity Bliss, said: "This is a very interesting piece of new research and we always welcome anything that has the potential to improve outcomes for babies born premature or sick.
"This is a cost-effective treatment and could reduce admissions to intensive care services, which are already working at high capacity levels.
"While the early results of this research show benefits to babies born with low blood sugars, it is clear there is more research to be done to implement this treatment."